Prospects of cancer cure by gene silencing

Abstract:

Gene silencing takes place during the transcription and translation processes when a particular disease causing gene is silenced, its expression is likely to be silenced leading no formation of concerned gene product. Generally "CANCER" results from an altered balance between cell proliferation, cell division and cell death.

So I am interested in designing those kind of anticancerious drugs which is dependent at gene silencing method the mechanism is that the drug is binds to the abnormal promoter of the abnormal cell DNA and initiates the normal growth resulting the altered  m-RNA is not formed  so protein will not formed out and phenotype had not changed Yet the information of beginning of uncontrolled cell division of a particular site may not sent to operon and ensuring the normal cell growth Gene  silencing is highly useful to making anticancerious drug or any other disease control drug which is initiated due to alteration in gene.

Stimulation of p53 is also involve in cancer research it is major role play in prevention of cancer.

Key word : Gene, Cancer, Translation